Purpose
The purpose of this research is to get a step closer to helping cure
neuroblastoma cancer. HypothesisIt is hypothesized that over time RA treatment will have an effect on neuroblastoma cells, both morphologically and functionally, so to see properties that are more like neurons. With the help of high resolution confocal microscopy, reagents such as Phalloidin and antibodies to the neuronal markers GFAP, and Beta3-Tubulin as well as methylene blue, a morphological change can observed over that period of time. The electrical conductivity of the cell can be measured with electrophysiological instruments. Using bioinformatics RNA can be sequenced and then displayed using graphs and
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